BILIRUBIN AUGMENTS CA2+ LOAD OF DEVELOPING BUSHY NEURONS BY TARGETING SPECIFIC SUBTYPE OF VOLTAGE-GATED CALCIUM CHANNELS

Bilirubin augments Ca2+ load of developing bushy neurons by targeting specific subtype of voltage-gated calcium channels

Abstract Neonatal brain is particularly vulnerable grand love red heart reposado tequila to pathological levels of bilirubin which elevates and overloads intracellular Ca2+, leading to neurotoxicity.However, how voltage-gated calcium channels (VGCCs) are functionally involved in excess calcium influx remains unknown.By performing voltage-clamp reco

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Assessment of Inheritance and Fitness Costs Associated with Field-Evolved Resistance to Cry3Bb1 Maize by Western Corn Rootworm

The western corn rootworm, Diabrotica virgifera virgifera LeConte, is among the most serious insect pests of maize in North America.One strategy used to manage this pest is transgenic maize that produces one or more crystalline (Cry) toxins derived from the bacterium Bacillus thuringiensis (Bt).To delay Bt resistance by insect pests, refuges of non

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A simplified technique to fabricate tissue bolus device to manage dose distribution in maxillectomy patient with orbital exenteration

The primary goal of radiotherapy is to deliver maximum dose to tumor but minimal dose to normal tissues.Irregular surfaces along with cavities sometimes make it difficult to deliver a homogenous radiation dose.Data incorporated click here in the delivery of prescribed dose are measured from the dosimetric system which are homogenous in nature, henc

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Predicting hospital admissions from individual patient data (IPD): an applied example to explore key elements driving external validity

Objective To explore factors that potentially impact external validation performance while developing and validating a prognostic model for hospital admissions (HAs) in flex 4 heartworm test complex older general practice patients.Study design and setting Using individual participant data from four cluster-randomised trials conducted in the Netherl

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